Final answer:
The muscles of mastication are innervated by the trigeminal nerve (CN V).
Step-by-step explanation:
The muscles of mastication are innervated by the trigeminal nerve (CN V). The trigeminal nerve is responsible for supplying sensory and motor innervation to the face, including the muscles used for chewing or mastication. This nerve plays a crucial role in allowing us to open and close our mouth, move our jaw, and perform actions like biting and chewing.