Final answer:
When addressing a school-age child with Down syndrome and bruising all over the body, the nurse should prioritize investigating the possibility of acute leukemia, a complication associated with the condition.
Step-by-step explanation:
When a school-age child with Down syndrome presents with bruising all over the body, it is crucial to first address a specific complication related to the condition. In this case, the nurse should first consider the increased risk of leukemia. Children with Down syndrome have a higher likelihood of developing acute leukemia than the average child, and this condition could account for the bruising observed.
Down syndrome is a genetic condition characterized by an extra copy of chromosome 21, leading to intellectual disability, muscle weakness, and a predisposition to certain medical conditions, including leukemia. While muscle hypotonia and hyperflexibility in children with Down syndrome may lead to falls that can cause bruising, and while any child is at risk for abuse or might have skin issues, the presentation of widespread bruising warrants an assessment prioritizing the possibility of leukemia due to its serious nature and need for prompt medical intervention.