Question

A nurse is reviewing the medication administration record of a client who has a history of Stevens-Johnson syndrome when taking sulfamethoxazole-trimethoprim. Which of the following medications should the nurse identify as contraindicated for this client?

A. Ciprofloxacin
B. Amoxicillin
C. Doxycycline
D. Nitrofurantoin

Answer 1

In a client with a history of Stevens-Johnson syndrome to sulfamethoxazole-trimethoprim, a medication containing sulfonamides is contraindicated. The medication from the given options that would be contraindicated is trimethoprim/sulfamethoxazole.

Step-by-step explanation:

A nurse reviewing the medication administration record for a client with a history of Stevens-Johnson syndrome when taking sulfamethoxazole-trimethoprim should recognize that any medication containing sulfonamides is contraindicated for this client due to the risk of hypersensitivity reactions. Therefore, among the listed options, the contraindicated medication would be:

• Trimethoprim/sulfamethoxazole

Other medications listed - ciprofloxacin, amoxicillin, doxycycline, and nitrofurantoin - do not contain sulfonamides. However, since the question provides these medications as options, the nurse must verify that none of the specific brand names or formulations of these medications include any sulfonamides. In standard formulations, ciprofloxacin does not contain sulfonamides and should not trigger Stevens-Johnson syndrome in patients with sulfonamide allergies.