Final answer:
Osteosarcoma is a malignant bone tumor with symptoms like pain, swelling, and bone weakness, managed with surgery, chemotherapy, and sometimes radiation. Risk factors include genetics and previous radiotherapy. Diagnosis is made through imaging tests and biopsy.
Step-by-step explanation:
Osteosarcoma is a type of malignant bone tumors that occurs when cells in the bone start to divide uncontrollably, forming a mass or tumor. These are generally found in the long bones of the body, such as the legs or arms, but can occur in any bone. Clinical manifestations of osteosarcoma include pain at the site of the tumor, swelling, and the presence of a palpable mass. In some cases, the affected bone may be weakened and more prone to fractures.
Management of osteosarcoma often involves a combination of treatments such as surgery to remove the tumor, chemotherapy to kill cancerous cells, and in some cases, radiation therapy. Since osteosarcoma can spread to other parts of the body, treatments aim to control the cancer's local and systemic effects.
Risk factors for osteosarcoma include certain genetic conditions, previous radiotherapy, and having a family history of the disease. Osteosarcoma is typically diagnosed using imaging tests such as X-rays, MRIs, CT scans, and a biopsy where a sample of the tumor is examined under a microscope.