Final answer:
Hemolytic Disease of the Newborn (HDN) is a type of anemia that occurs when antibodies produced by a Rh-negative mother destroy the red blood cells of a Rh-positive fetus. Treatment for HDN involves administering Rho(D) immune globulin to the mother to prevent the formation of anti-D antibodies and subsequent destruction of fetal red blood cells.
Step-by-step explanation:
Hemolytic Disease of the Newborn (HDN) is a type of anemia that occurs when antibodies produced by a Rh-negative mother destroy the red blood cells of a Rh-positive fetus. This condition is caused by a type II hypersensitivity reaction in which maternal anti-Rh antibodies cross the placenta and target fetal Rh+ red blood cells for lysis. Manifestations of HDN can range from mild to severe and may include anemia, jaundice, enlarged liver and spleen, and brain damage. Treatment for HDN involves administering Rho(D) immune globulin to the mother to prevent the formation of anti-D antibodies and subsequent destruction of fetal red blood cells.