Final answer:
Osteogenesis imperfecta is a genetic disorder that affects bone development and repair. It is characterized by fragile and easily fractured bones. Management involves minimizing fractures and improving mobility.
Step-by-step explanation:
Osteogenesis imperfecta (OI) is a genetic disorder that affects bone development and repair. It is caused by a defective gene that results in insufficient production of collagen, which is necessary for building strong bones. OI is characterized by fragile and easily fractured bones.
There are several classifications of OI based on the severity of the disease. Type-I presents in early infancy with fractures, while Type-II is more severe and leads to fetal death. Other manifestations of OI include bone deformities, short stature, bowing of the long bones, curvature of the spine, and breathing difficulties.
Management of OI focuses on minimizing fractures and improving mobility. Treatment options include safe exercises, physical therapy, assistive devices, and medications to improve bone density.