Final Answer:
Leukoplakia has a higher risk of malignant transformation in smokers.
Therefore, correct option is A. Has a higher risk of malignant transformation in smokers.
Step-by-step explanation:
Leukoplakia is a white patch or plaque that cannot be attributed to any other specific cause such as infection or trauma. While it is associated with a higher risk of malignant transformation in smokers, accounting for a significant proportion of oral cancers, the mere presence of leukoplakia does not provide a definitive diagnosis of malignancy. The transformation into malignancy is influenced by factors such as smoking, and regular monitoring and biopsy are often necessary to assess the risk of progression.
Interestingly, some cases of leukoplakia may have a lower risk of malignancy when they exhibit red components, a variant known as erythroleukoplakia. The presence of mixed red components may indicate a different biological behavior and alter the risk profile.
Therefore, correct option is A. Has a higher risk of malignant transformation in smokers.