Final answer:
The nurse should advise the patient that sildenafil cannot be used if they are taking nitroglycerin, due to the risk of severe hypotension. Patients with heart conditions or those on nitrates should consult with their physician before using sildenafil for ED treatment.
Step-by-step explanation:
The correct response to the question about the nurse's advice when caring for a patient requesting sildenafil for erectile dysfunction (ED) is 'You will not be able to use sildenafil if you are taking nitroglycerin.' The use of sildenafil, which is a PDE5 inhibitor, is contraindicated with nitroglycerin due to the risk of severe hypotension. Sildenafil was originally investigated for hypertension and angina, and was later approved by the FDA for the treatment of ED. There have been reports of deaths among at-risk users, particularly those with cardiac disease who are taking nitrates. Therefore, it is critical for individuals with cardiac conditions or those on medications such as nitrates to consult their physician before starting ED treatment with sildenafil.