Final answer:
The nurse should prioritize meticulous hand hygiene for a patient with a low absolute neutrophil count, such as 440/mm3, even if there are no signs of infection.
Step-by-step explanation:
If a patient's absolute neutrophil count (ANC) is low, such as 440/mm3, they are considered to be neutropenic and at higher risk for infections. Despite the patient showing no signs or symptoms of infection, the nurse should prioritize meticulous hand hygiene when providing care for this patient. This is essential to minimize the risk of transmitting potential pathogens to the neutropenic patient. While the timely administration of antibiotics is crucial when an infection is suspected or diagnosed, it may not be the immediate action for a patient without signs of infection. A nutrient-dense diet and maintaining a sterile care environment are supportive measures that would benefit patient well-being but do not take priority over hand hygiene in the absence of infection. Neutrophils are key components of the innate immune system, serving as frontline defenders against infections, which is why meticulous hand hygiene is imperative.