Final answer:
The statement is false; high levels of HDLs are beneficial and help reduce the risk of coronary artery disease by transporting excess cholesterol back to the liver, thus preventing the formation of artery-clogging plaque.
Step-by-step explanation:
The statement that high blood levels of HDLs are associated with an increased risk of coronary artery disease is false. HDLs, or high-density lipoproteins, are often referred to as "good" cholesterol because they aid in removing excess cholesterol from the bloodstream and the arterial walls. HDLs help transport surplus cholesterol back to the liver for recycling, which prevents the formation of plaque on the artery walls. In contrast, LDLs, or low-density lipoproteins, are considered "bad" cholesterol because when their levels are high, cholesterol can build up and form plaque in the arteries, leading to atherosclerosis, which is a significant risk factor for coronary artery disease. A good balance with low LDL and high HDL levels is important for cardiovascular health.