Final answer:
MRSA is a significant multi-drug resistant organism found in hospitals and community settings that concerns medical professionals due to its potential to become a 'superbug' resistant to many antibiotics.
Step-by-step explanation:
Multi-drug resistant organisms that are prevalent in hospitalized patients and community settings include Methicillin-resistant Staphylococcus aureus (MRSA), Streptococcus pneumoniae, Escherichia coli (E. coli), and other pathogens. Among these, MRSA is significant due to its ability to cause serious infections and its resistance to a wide range of antibiotics. The ESKAPE pathogens are a group of multi-drug resistant microbes that are of clinical concern, as they can 'escape' the effects of conventional antibiotics. Medical professionals are particularly concerned about MRSA because it signifies the potential for bacteria to acquire additional resistance genes and become 'superbugs' that are difficult to treat. This is problematic because MRSA can transfer methicillin-resistance to other bacteria, patients may not be treated with the correct antibiotics rapidly enough, and it has the potential to acquire additional antibiotic resistance genes.