Final answer:
The most appropriate diagnosis is delirium due to another medical condition.
Step-by-step explanation:
The most appropriate diagnosis for the previously healthy 67-year-old man with acute change in mental status is delirium due to another medical condition. Delirium is characterized by disruptions in memory, confusion, difficulty with tasks, poor judgment, and personality changes. In this case, there is no evidence of substance intoxication or withdrawal, and no other medical problems identified, indicating that the delirium is likely due to an underlying medical condition.