Question

The nurse is assessing a patient who has a new prescription for vorapaxar (Zontivity). Which of these conditions are considered contraindications to the use of vorapaxar? select all that apply

a. Impaired renal function
b. Impaired liver function
c. History of myocardial infarction
d. Peripheral artery disease
e. History of stroke

Answer 1

Contraindications for vorapaxar (Zontivity) include impaired liver function and a history of stroke, which increase the risk of bleeding complications. It is not contraindicated in patients with impaired renal function, history of myocardial infarction, or peripheral artery disease.

Step-by-step explanation:

The nurse is assessing a patient who has a new prescription for vorapaxar (Zontivity). The conditions that are considered contraindications to the use of vorapaxar include:

• Impaired liver function
• History of stroke
• Active pathological bleeding

Vorapaxar is an antiplatelet medication that is used to reduce the risk of heart attack, stroke, and cardiovascular death in patients with a history of heart disease. However, vorapaxar is not recommended for patients with impaired liver function or a history of stroke due to an increased risk of bleeding. It is also contraindicated in patients with active pathological bleeding. There is no contraindication listed for impaired renal function or peripheral artery disease in relation to vorapaxar use. In fact, vorapaxar may be prescribed to patients with a history of myocardial infarction and peripheral artery disease to prevent thrombotic events. Therefore, the correct answers are b 'Impaired liver function' and e 'History of stroke.'