Final answer:
The potential concern in a patient taking spironolactone is a serum potassium level of 5.8 mEq/L, indicating hyperkalemia, which is above the normal range and can be dangerous.
Step-by-step explanation:
When a nurse is checking the laboratory data for a patient taking spironolactone (Aldactone), the result that would cause potential concern is a serum potassium level of 5.8 mEq/L. Spironolactone is a potassium-sparing diuretic, which can lead to hyperkalemia (elevated potassium levels). Normal serum potassium levels are generally between 3.6 to 5.2 mEq/L. Aldosterone, a hormone that spironolactone antagonizes, normally helps to regulate potassium levels by increasing its excretion. Therefore, the use of spironolactone can reduce aldosterone's effect and potentially cause an unhealthy increase in blood potassium.