Question

The nurse is teaching a class on how red blood cell formation is regulated by the body to a group of clients who have AIDS. The nurse evaluates that learning has occurred when the clients make which statements?

Select all that apply.
1. "Red blood cell formation is regulated through chemicals called colony-stimulating factors that come from white blood cells."
2. "Red blood cell formation is regulated through messages from the hormone, secretin, which is located in the kidney."
3. "Red blood cell formation is regulated through specific liver enzymes and a process called hemochromatosis."
4. "Red blood cell formation is regulated through messages from the hormone erythropoietin."
5. "Red blood cell formation is regulated through specific transporter proteins called apolipoprotein A and B."

Answer 1

Red blood cell formation is regulated through erythropoietin, a hormone from the kidneys, and colony-stimulating factors. The regulation involves a negative feedback loop where the release of erythropoietin is decreased when enough red blood cells are present.

Step-by-step explanation:

The nurse is conducting a class on how red blood cell formation is regulated in the body, particularly for patients with AIDS. Learning would be evaluated as having occurred when the clients understand that red blood cell formation is primarily regulated through messages from the hormone erythropoietin, which is secreted by the kidneys in response to low oxygen levels in the blood. Additionally, clients should recognize that colony-stimulating factors, which can come from white blood cells among other sources, play a role in the proliferation and differentiation of formed elements in the blood, including red blood cells.

Specifically, correct statements reflecting the clients' learning would include:

• "Red blood cell formation is regulated through chemicals called colony-stimulating factors that come from white blood cells." - This statement is correct as colony-stimulating factors are involved in the differentiation and proliferation of blood cells.
• "Red blood cell formation is regulated through messages from the hormone erythropoietin." - This statement is correct as erythropoietin is a key hormone responsible for the production of red blood cells.

The statements about secretin in the kidneys, liver enzymes and hemochromatosis, and specific transporter proteins (apolipoprotein A and B) are incorrect in the context of red blood cell formation.

It is also important to note that the regulation of erythropoietin follows a negative feedback loop, as when there is an adequate number of red blood cells present in the blood, the release of erythropoietin from the kidney decreases.