Final answer:
The primary concern for a hypertensive female patient who becomes pregnant is the use of ACE inhibitors such as Enalapril (Vasotec). These medications can cause harm to the developing fetus and should be avoided during pregnancy.
Step-by-step explanation:
When considering a hypertensive female patient who becomes pregnant, the primary concern would be the use of ACE inhibitors such as Enalapril (Vasotec). ACE inhibitors have been associated with fetal renal failure, oligohydramnios, pulmonary hypoplasia, limb contracture, and cranial bone abnormalities. These medications should be avoided during pregnancy due to their potential harm to the developing fetus.