Final answer:
The most significant lab result for a patient on hydrochlorothiazide (HydroDIURIL) and digoxin (Lanoxin) is a Potassium level of 2.9 mEq/L due to the risk of digoxin toxicity exacerbated by hypokalemia.
Step-by-step explanation:
The lab result that would be most significant for a patient receiving hydrochlorothiazide (HydroDIURIL) and digoxin (Lanoxin) is a Potassium level of 2.9 mEq/L. Hydrochlorothiazide is a thiazide diuretic which can lead to the depletion of electrolytes, including potassium. Low potassium levels, also known as hypokalemia, can significantly increase the risk of digoxin toxicity because digoxin affects the sodium-potassium ATPase pump, which is highly sensitive to potassium concentrations. Therefore, monitoring potassium levels is critical in patients taking both of these medications to avoid potentially serious side effects.