Question

A patient who sustained a leg laceration in an industrial accident is brought to the emergency department. The area around the laceration is red, swollen, and tender. Which substance is responsible for causing this response?

1)Histamine

2) Prostaglandin

3) Bradykinin

4) Serotonin

Answer 1

Bradykinin is responsible for causing the redness, swelling, and tenderness around a leg laceration.

Step-by-step explanation:

The substance responsible for causing the redness, swelling, and tenderness around a leg laceration is bradykinin. When tissue is injured, damaged cells release inflammatory chemical signals that cause vasodilation, or widening of the blood vessels. This increased blood flow results in redness and heat at the wound site. Bradykinin is one of the inflammatory mediators released during tissue injury, and it contributes to the vasodilation, edema (swelling), and pain associated with inflammation.