Normal Hemoglobin mRNA:
The specific base sequence for these amino acids is: GTG/CAC/CTG/ACT/CCT/GAG. Sickle cell hemoglobin (Hemoglobin S) results when, glutamic acid that is normally present in the sixth position on the beta globin chain is substituted with valine.
Normal hemoglobin Amino Acid:
The specific base sequence for these amino acids is: GTG/CAC/CTG/ACT/CCT/GAG. Sickle cell hemoglobin (Hemoglobin S) results when, glutamic acid that is normally present in the sixth position on the beta globin chain is substituted with valine
Sickle cell hemoglobin mRNA:
The mutation that causes sickle cell disease is the substitution of an A for a T in the hemoglobin gene. A CTT sequence in the gene normally codes for GAA in its messenger RNA. GAA in the messenger RNA specifies the amino acid glutamic acid at a particular position in normal hemoglobin.moglobin mRNA: The specific base sequence for these amino acids is: GTG/CAC/CTG/ACT/CCT/GAG. Sickle cell hemoglobin