Question

Anticipation is the finding in a genetic disorder that:

A Mutations in the promoter are more severe than those in exons
B One is more likely to diagnose genetic disease in additional family members once a family is referred for genetic counseling
C The severity of phenotype increases, and age of onset decreases as some genetic disorders are passed through families
D The known variability in a disease phenotype increases once a disorder is described in the literature because of better clinical observation
E For many complex traits, the likelihood of having an affected child increases the risk of having a second affected child

Answer 1

Anticipation in genetic disorders refers to the increasing severity of symptoms and earlier onset in subsequent generations of a family.

Step-by-step explanation:

Anticipation is the finding in a genetic disorder that the severity of phenotype increases, and age of onset decreases as some genetic disorders are passed through families. This means that the symptoms of the disorder become more severe and appear at an earlier age in each generation of a family.