Final answer:
When caring for a hospitalized patient receiving ondansetron, it is appropriate to assess for headache, as this is a potential side effect of the medication.
Step-by-step explanation:
Ondansetron, commonly known as Zofran, is a medication used to prevent nausea and vomiting associated with cancer chemotherapy, radiation therapy, or surgery. When caring for a hospitalized patient receiving ondansetron, it is appropriate nursing action to assess for headache, as headaches can be a side effect of this medication. The nurse should monitor the patient's response to the drug, watch for any signs of adverse effects, and provide comfort measures to alleviate any headaches or other discomforts the patient may experience. Keeping the head of the bed flat is not a necessary action specific to ondansetron administration, and there is no need to place a sign on the door to restrict fluids unless indicated by the patient's condition or doctor's orders.