Question

Which of the following statements accurately describes the physiological and pharmacological effects of estrogen and progesterone on bone mineral reabsorption in premenopausal and postmenopausal women?

Option 1: Estrogen and progesterone block bone mineral reabsorption in premenopausal women, preventing osteoporosis, while postmenopausal women experience increased reabsorption leading to osteoporosis.

Option 2: Estrogen and progesterone enhance bone mineral reabsorption in premenopausal women, preventing osteoporosis, while postmenopausal women experience reduced reabsorption leading to osteoporosis.

Option 3: Estrogen and progesterone have no significant impact on bone mineral reabsorption in premenopausal women, and both groups are equally susceptible to osteoporosis postmenopausally.

Option 4: Estrogen and progesterone inhibit bone mineral reabsorption in both premenopausal and postmenopausal women, protecting against osteoporosis in both stages of life.

Answer 1

Estrogen and progesterone block bone mineral reabsorption in premenopausal women and increase reabsorption in postmenopausal women, leading to osteoporosis.

Step-by-step explanation:

Option 1: Estrogen and progesterone block bone mineral reabsorption in premenopausal women, preventing osteoporosis, while postmenopausal women experience increased reabsorption leading to osteoporosis.