Question

First-generation (older) histamine H1 blockers such as diphenhydramine, phenothiazine anti-psychotic drugs (eg, chlorpromazine), and tricyclic antidepressants (eg, imipramine) have pharmacologic actions, side effects, toxicities, and contraindications that are very similar to those of which other drug? a. Atropine

b. Bethanechol
c. Isoproterenol
d. Neostigmine
e. Propranolol

Answer 1

The pharmacologic actions and side effects of older histamine H1 blockers, phenothiazine anti-psychotics, and tricyclic antidepressants are very similar to those of atropine, an anticholinergic drug.

Step-by-step explanation:

First-generation (older) histamine H1 blockers such as diphenhydramine, phenothiazine anti-psychotic drugs (e.g., chlorpromazine), and tricyclic antidepressants (e.g., imipramine) have pharmacologic actions, side effects, toxicities, and contraindications that are very similar to those of the drug atropine. Atropine is a standard anticholinergic drug that acts as an antagonist to muscarinic acetylcholine receptors, blocking the effects of excess acetylcholine. These medications, despite their primary uses, share anticholinergic properties, causing them to have similar side effects such as dry mouth, constipation, blurred vision, and sedation.