Question

Cooling and flushing of pancreas, liver, and kidneys of cadaver donors are accomplished by cannulation of the organ and infusion of large amounts of cold:

a) Normal saline
b) Ringer's lactate
c) Hypertonic saline
d) University of Wisconsin solution

Answer 1

For the preservation of pancreas, liver, and kidneys in cadaver donors, the University of Wisconsin solution is used instead of regular isotonic solutions like normal saline or lactated Ringer's, due to its special formulation designed for organ preservation.

Step-by-step explanation:

Organ Preservation in Cadaver Donors

When preserving the pancreas, liver, and kidneys of cadaver donors, flushing and cooling are essential processes. These procedures are usually carried out by cannulation of the organ followed by the infusion of cold preservation solutions. The appropriate solution for this purpose is not regular intravenous isotonic solutions like normal saline or lactated Ringer's, which are typically used for fluid replacement in dehydrated patients because they match the osmolarity of the body's fluids and prevent red blood cell destruction. Instead, specialized solutions like the University of Wisconsin solution are preferred. This solution has been specifically formulated to preserve organs for transplantation by providing the necessary nutrients and by minimizing cellular damage caused by cold ischemia.