Question

Infants who suffer from DiGeorge's syndrome:

a. Have high levels of IgG compared to IgM
b. Are unable to make antibodies
c. Have low number of B cells
d. Do not mediate effective isotype switching in their B cells

Answer 1

Infants with DiGeorge's syndrome have low number of B cells.

Step-by-step explanation:

Infants who suffer from DiGeorge's syndrome have low number of B cells. This is because DiGeorge's syndrome is a genetic disorder that affects the development of the immune system, specifically the thymus gland. The thymus gland is responsible for the maturation of T cells, which are important for activating B cells to produce antibodies. Since B cells require T cells for activation, low numbers of B cells can result in an inability to produce antibodies, making option c. the correct answer.