Final answer:
True, the skin with an average surface area of about 2 m² and a weight around 10 lbs. is the largest organ of the human body, integral to the integumentary system.
Step-by-step explanation:
The statement that the skin is the largest organ of the human body, with an average surface area of about 2 m² and a weight of around 10 lbs., is true.
As part of the integumentary system, which also includes hair and nails, the skin serves not just as an organ but also as a vital barrier protecting the body against pathogens and external damage. It is composed of layers, such as the epidermis and dermis, loaded with various structures including blood vessels, sweat glands, nerve endings, and pigment-producing cells within a thin stack just 2 mm thick.