Question

In a dog with acute anemia due to hemorrhage or hemolysis, when does evidence of regeneration (polychromasia and reticulocytosis) begin to become evident in the peripheral blood?

A. within 1 hour
B. within 30 minutes
C. within 3 days
D. never

Answer 1

Evidence of regeneration in the form of polychromasia and reticulocytosis in a dog with acute anemia typically becomes evident in the peripheral blood within 3 days.

Step-by-step explanation:

In a dog experiencing acute anemia due to hemorrhage or hemolysis, regeneration evidence in the form of polychromasia and reticulocytosis begins to appear in the peripheral blood typically within 3 days (C). The body's response to anemia includes increasing the production of reticulocytes, which are immature red blood cells (RBCs), that are released into the bloodstream and mature into erythrocytes. These erythrocytes normally circulate for an average of 120 days before being removed by macrophages in the bone marrow, liver, and spleen.