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Listed below are sigma subdomains followed by its function. Which of the following pairings has an incorrect function assigned?

A) 3.0; contacts upstream sequence in the extended TATA box
B) 1.2; contacts discriminator element
C) 2.1/2.2; recognizing conserved region in RNAP core
D) 2.3; contacts alpha CTD

User Trevor V
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1 Answer

5 votes

Final answer:

The incorrect function pairing is A) 3.0; contacts upstream sequence in the extended TATA box.

Step-by-step explanation:

The incorrect function pairing is A) 3.0; contacts upstream sequence in the extended TATA box. Sigma subdomain 3.0 is responsible for recognizing the -10 and -35 sequences in the promoter region, not the upstream sequence in the extended TATA box. The upstream sequence in the extended TATA box is recognized by sigma subdomain 2.3.

User Vkraemer
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