Question

Which of the following glucose transporters has properties that facilitate glucose transport out of human liver cells to maintain blood sugar level homeostasis?

A) GLUT1
B) GLUT2
C) GLUT3
D) GLUT4
E) GLUT5

Answer 1

GLUT2 is the glucose transporter facilitating glucose transport out of human liver cells to regulate blood sugar levels, enabling glucose homeostasis.

Step-by-step explanation:

The glucose transporter that has properties facilitating glucose transport out of human liver cells to maintain blood sugar level homeostasis is GLUT2. GLUT2 is a low-affinity transporter in the liver and pancreatic cells that helps maintain glucose homeostasis by enabling glucose to move in and out of cells, depending on the body's metabolic needs. When the blood sugar level is high, liver cells take in glucose and convert it into glycogen for storage. Conversely, when the blood sugar level is low, these cells break down glycogen and release glucose back into the bloodstream, a process known as glycogenolysis. Importantly, of the options provided, GLUT2 is the protein that typically enables glucose efflux from the liver to regulate blood glucose levels.