Final answer:
During DNA replication, mistakes are corrected by DNA polymerase through proofreading. Pol III is primarily involved in replication, while pol I and pol II are involved in repair and can also initiate replication in certain cases. Pol I and pol II perform error-prone DNA repair, deliberately making mistakes for genetic diversity.
Step-by-step explanation:
During DNA replication, most mistakes are corrected by the proofreading ability of DNA polymerase itself. The DNA polymerase reads the newly added base before adding the next one, ensuring correct pairings. If an incorrect base is added, the DNA polymerase cuts and removes the wrong nucleotide. This is performed by the exonuclease action of DNA polymerase III (pol III).
DNA polymerase I (pol I) and DNA polymerase II (pol II) are primarily involved in repair. However, pol I can also initiate replication in certain cases. Pol I and pol II perform error-prone DNA repair, deliberately making mistakes to introduce genetic diversity in certain situations.