Question

The serologic markers in expected order of appearance in the serum of a patient with Hepatitis B infection are?

A. HBsAg, HBeAg, HBcAb, HBeAb, and HBsAb
B. HBeAg, HBcAg, HBsAg, HBsAb, and HBcAb
C. HBcAg, HBeAg, HBcAb, HBsAb, and HBsAg
D. HBcAg, HBsAb, HBeAg, HBsAg, and HBcAb

Answer 1

The serologic markers in the expected order of appearance in the serum of a patient with Hepatitis B infection are HBsAg, HBeAg, HBcAb, HBeAb, and HBsAb.

Step-by-step explanation:

The correct order of appearance of serologic markers in the serum of a patient with Hepatitis B infection is:

1. HBsAg (Hepatitis B surface antigen)
2. HBeAg (Hepatitis B e antigen)
3. HBcAb (Hepatitis B core antibody)
4. HBeAb (Hepatitis B e antibody)
5. HBsAb (Hepatitis B surface antibody)

This order of appearance reflects the different stages of the infection:

• HBsAg is the earliest marker to appear and indicates the presence of the virus in the body.
• HBeAg appears shortly after HBsAg and indicates active viral replication.
• HBcAb appears after the immune response begins, indicating ongoing infection.
• HBeAb appears as the immune response progresses and viral replication decreases.
• HBsAb is the last marker to appear and indicates long-term immunity or recovery from the infection.