Question

Which statement is MOST ACCURATE in terms of the signal (leader) sequence of preproinsulin?

Option 1: It guides the protein to the endoplasmic reticulum.
Option 2: It directs the protein to the lysosomes.
Option 3: It is involved in nuclear transport.
Option 4: It functions in cytoplasmic translation.

Answer 1

The signal (leader) sequence of preproinsulin guides the protein to the endoplasmic reticulum.

Step-by-step explanation:

The MOST ACCURATE statement in terms of the signal (leader) sequence of preproinsulin is Option 1: It guides the protein to the endoplasmic reticulum.

The signal sequence is a short tail of amino acids that directs a protein to a specific cellular compartment. In the case of preproinsulin, the signal sequence guides the protein to the endoplasmic reticulum, where further modifications and processing of the protein occur.