Final answer:
The correct answer is d. drug bound to plasma albumin and transported to the site of action. Pharmacologic responses can only be elicited by a drug that is bound to plasma albumin and transported to the site of action.
Step-by-step explanation:
The correct answer is d. drug bound to plasma albumin and transported to the site of action. Pharmacologic responses can be elicited only by a drug that is bound to plasma albumin and transported to the site of action. Plasma protein binding affects the distribution of a drug in the body and only the unbound drug is available to cross membrane barriers and exert pharmacological effects.