Final answer:
The route of administration is crucial as it affects drug absorption, notably when oral intake does not permit sufficient absorption for therapeutic effects, necessitating alternative methods such as intravenous injections.
Step-by-step explanation:
False. The route of administration significantly influences drug absorption. Oral administration is convenient, but it is not always effective for certain drugs, as they might not be well-absorbed from the gastrointestinal (GI) tract. For these drugs, parenteral routes such as intravenous or intramuscular injection can lead to higher plasma levels and are more suitable for certain medical conditions and treatments. Intravenous delivery, for example, can be essential when high blood concentrations of a drug are necessary, such as in treating infections. Drugs like bacitracin, polymyxin, and some antifungals are made into topical preparations since they are for treating superficial skin infections and are not easily absorbed when taken orally.