Final answer:
The ureters can be compressed or blocked by retroperitoneal fibrosis, a condition that forms extra fibrous tissue in the area where the ureters are located, potentially causing urine flow obstruction and kidney issues.
Step-by-step explanation:
The ureters are frequently affected by retroperitoneal fibrosis, a condition that occurs when extra fibrous tissue forms in the area behind the stomach and intestines, where the ureters are located. This tissue can cause the ureters, which are tubes that carry urine from the kidneys to the bladder, to be compressed or blocked. As a result, the flow of urine may be obstructed leading to conditions like hydronephrosis and potentially causing chronic kidney disease if the obstruction is not relieved.
Retroperitoneal fibrosis is often associated with a chronic inflammatory response that can lead to the development of a tough fibrotic mass. This mass can envelop structures such as the renal fascia and ureters, particularly where they are retroperitoneally located. The disease may be idiopathic, meaning its cause is unknown, or it may be associated with certain medications, infections, surgeries, or autoimmune conditions. Symptoms might not be apparent in the early stages but can include flank pain, lower back pain, or signs of kidney impairment as it progresses.
Diagnostic imaging, such as ultrasound, CT, or MRI scans, is commonly used to identify the extent of fibrosis and its effect on the ureters. Treatment usually involves managing the underlying cause, relieving the ureteral obstruction, and in some cases, surgery may be necessary to remove the fibrotic tissue.