Final answer:
Lyme disease does not have to be reported to the National Notifiable Disease Surveillance System of the CDC.
Step-by-step explanation:
The disease that does not have to be reported to the National Notifiable Disease Surveillance System of the CDC is Lyme disease.
The National Notifiable Disease Surveillance System (NNDSS) compiles data on certain infectious diseases, called notifiable diseases, from state and local health agencies in the United States. These diseases are considered to be of public health importance and must be reported to the CDC. Examples of notifiable diseases include tuberculosis (TB), measles, and COVID-19.
Lyme disease, on the other hand, is not required to be reported to the NNDSS. It is a tick-borne disease caused by the bacterium Borrelia burgdorferi and can cause a variety of symptoms, including fever, fatigue, and joint pain. While Lyme disease is tracked by public health agencies, it is not considered a notifiable disease.