Final answer:
Phosphorylation occurs in the two-component regulatory system when IK-B, an inhibitor protein, gets phosphorylated, allowing NF-KB to enter the nucleus and initiate RNA transcription. This phosphorylation inactivates the inhibitor and activates gene transcription.
Step-by-step explanation:
Phosphorylation occurs in the two-component regulatory system when a protein becomes phosphorylated. Phosphorylation occurs in the two-component regulatory system when IK-B, an inhibitor protein, gets phosphorylated, allowing NF-KB to enter the nucleus and initiate RNA transcription. This phosphorylation inactivates the inhibitor and activates gene transcription.
In this system, the protein that gets phosphorylated is the inhibitor protein called IK-B. When IK-B is phosphorylated, it can no longer bind to the regulatory protein NF-KB. This allows NF-KB to enter the nucleus and initiate RNA transcription, activating the process of transcription. Phosphorylation of IK-B by protein kinase C (PKC) inactivates the inhibitor and enables the activation of gene transcription.