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What is the main importane of pump in maintaining membrane potential

User ColinMD
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Final answer:

The sodium-potassium pump is pivotal in maintaining the membrane potential by actively transporting Na+ out and K+ in, using ATP. This creates an electrochemical gradient essential for nerve impulse transmission and muscle contraction, and enables secondary transport crucial for cellular functions.

Step-by-step explanation:

The main importance of the sodium-potassium pump (Na+/K+ ATPase) in maintaining membrane potential lies in its role in active transport. This pump uses energy from ATP hydrolysis to move three sodium ions (Na+) out of the cell and two potassium ions (K+) into the cell. This movement creates an electrochemical gradient across the cell membrane, which is essential for various cellular functions, such as nerve impulse transmission and muscle contraction.

During cell excitation and normal functioning, the balance of these ions can be disturbed, necessitating the action of the pump to restore the balance and maintain the specific concentration gradients. As a result, the resting membrane potential is preserved, typically at around -70 mV inside the neuron relative to the outside. This negative charge is critical for the conduction of nerve impulses and other cellular activities.

Furthermore, the pump contributes to secondary active transport, which allows other substances such as amino acids and glucose to enter the cell, using the energy stored in the electrochemical gradient. The perpetuation of the sodium-potassium pump activity is so crucial to certain cells like neurons that a significant portion of cellular energy is devoted to it.

User Bukes
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