Final answer:
Pepsin is not used to treat Gonorrhoea as it is an enzyme, not an antibiotic. Gonorrhoea, a bacterial infection, requires specific antibiotics for treatment, and resistance has led to recommendations for a combination therapy of ceftriaxone and azithromycin.
Step-by-step explanation:
Pepsin cannot be used to treat Gonorrhoea because it is not an antibiotic; it is an enzyme that breaks down proteins in the stomach. Gonorrhoea, caused by the bacterium Neisseria gonorrhoeae, needs to be treated with specific antibiotics to effectively curtail the bacterial infection. Over time, this bacterium has developed resistance to many antibiotics, and now a combination therapy is widely recommended. The Centers for Disease Control and Prevention (CDC) currently recommends a dual therapy of ceftriaxone and azithromycin to address this issue and the common co-infection with Chlamydia trachomatis.
The rise of antibiotic-resistant bacteria like N. gonorrhoeae has necessitated changes in treatment protocols. Antibiotic resistance poses a major global challenge as it can lead to treatment failures and the spread of infections.