8.1k views
1 vote
What muscular enzyme dominates adenine nucleotide in skeletal muscle?

User Cheruvian
by
7.4k points

1 Answer

3 votes

Final answer:

The enzyme that dominates adenine nucleotide in skeletal muscle is CPK (Creatine Phosphokinase), with ATPase also playing a critical role. These enzymes help regenerate ATP, essential for muscle contraction.

Step-by-step explanation:

The muscular enzyme that dominates adenine nucleotide in skeletal muscle is CPK (Creatine Phosphokinase), which catalyzes the conversion of creatine to creatine phosphate. During muscle contraction, CPK provides a quick supply of energy by regenerating ATP from ADP, playing a critical role in maintaining energy levels in skeletal muscles. Another key enzyme is ATPase, critical for hydrolyzing ATP to ADP and necessary for muscle contraction and relaxation. Additionally, in skeletal muscle, the isoenzyme form LDH5 or M4, which has a low Km value for pyruvate, indicates a high affinity and thus a high rate of conversion of pyruvate to lactate, a process that also helps to generate ATP in the absence of oxygen.

Muscle contraction is a highly energy-demanding process, where ATP is broken down. As ATP is rapidly depleted during muscle activity, it must be quickly replenished through mechanisms like creatine phosphate metabolism, anaerobic glycolysis, and aerobic respiration. The high demand for ATP in skeletal muscles also explains the presence of enzymes that help in the fast regeneration of ATP from other high-energy compounds like creatine phosphate.

User Lungj
by
6.7k points