133k views
3 votes
What is the major difference between purine and pyrimidine synthesis in terms of when the ring is added? Both types of synthesis have a common molecule, what is it?

User Fons
by
8.8k points

1 Answer

3 votes

Final answer:

The major difference between purine and pyrimidine synthesis is that purine rings are assembled directly on the ribose sugar, while pyrimidine rings are made first and later attached to the ribose. Purines have a double ring structure, while pyrimidines have a single ring, both involving nitrogen atoms. The common molecule in both processes is the pentose sugar.

Step-by-step explanation:

The major difference between purine and pyrimidine synthesis is in the timing of the formation of the rings. In purine synthesis, the ring structure is built one atom at a time onto the ribose sugar, meaning the purine ring is assembled directly on the ribose. However, in pyrimidine synthesis, the ring is made first and then attached to the ribose sugar. Both purines and pyrimidines are essential components of nucleic acids, with purines including adenine and guanine and featuring a double ring structure made of a six-membered ring fused to a five-membered ring.

Pyrimidines, which include cytosine, thymine, and uracil, have a single six-membered ring structure. The common molecule in both purine and pyrimidine synthesis is the pentose sugar, which is present in the nucleotides that make up DNA and RNA.

Purines and pyrimidines are heterocyclic aromatic compounds, both containing nitrogen within their cycles, but they differ in the complexity of those rings. Purine is bicyclic, while pyrimidine is monocyclic. Each nitrogenous base is then attached to a pentose sugar molecule, where a molecule of water is removed to form a bond, creating the nucleotides essential for DNA and RNA.

User Yehonatan
by
7.3k points