Final answer:
Genetics and diet type would be confounded if all rats from Litter 1 were fed only Diet A, because differences in weight gain could be due to genetic variations rather than the diet, thus biasing the results of the nutrition experiment.
Step-by-step explanation:
If the 10 rats from Litter 1 were only fed Diet A, it would create a problem where genetics and type of diet would be confounded in the experiment. This confounding would occur because any observed differences in weight gain between the two groups of rats could be attributed to either the genetic background of the rats (since they come from different litters) or the diet they are being fed, making it difficult to isolate the effect of the diet on weight gain. A proper experiment design would involve randomly allocating rats from both litters to each diet to ensure that genetic differences are evenly distributed and do not bias the results.