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which experimental observations support the idea that aging is due to accumulation of cellular damage?

User Trunkc
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DNA damage studies illuminate how cellular repair processes impact aging, revealing how errors and stress responses contribute to the complex dance of time.

Studies on DNA damage and repair mechanisms reveal how these processes influence the aging process. By analyzing how different types of damage accumulate and affect cellular function, we gain insights into:

Cellular stress response: Understanding how cells respond to different DNA lesions helps us identify key pathways involved in aging.

Error accumulation: Investigating how repair mechanisms become less efficient with age sheds light on how errors in DNA replication contribute to aging phenotypes.

Epigenetic changes: Studying how damage can alter DNA methylation patterns, which regulate gene expression, provides clues about age-related changes in cellular function.

In short, understanding DNA damage and repair systems provides a crucial lens through which to view the complex interplay between cellular damage and the aging process.

Question:-

How do studies on DNA damage and repair mechanisms contribute to our understanding of the role of cellular damage in aging?

User Malina
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