Final answer:
The Medici family, particularly Cosimo de' Medici, were the main patrons of Donatello, Botticelli, and Michelozzo di Bartolomeo, supporting the efflorescence of Renaissance art in Florence.
Step-by-step explanation:
The patrons of Donatello, Botticelli, and Michelozzo di Bartolomeo were the Medici family, a prominent and influential family in Florence during the Renaissance. In particular, Cosimo de' Medici, the patriarch of the Medici dynasty, was known to sponsor Donatello. Cosimo was a considerable patron of the arts, encouraging the cultural movement that marked the Renaissance. Moreover, works by Botticelli and other artists were also commissioned by the Medici family, showcasing their broad patronage across various artists and contributing to the remarkable proliferation of art and culture during the period.
The final answer in a two-line explanation is: The patron for Donatello, Botticelli, and Michelozzo di Bartolomeo was the Medici family. Specifically, Donatello was sponsored by Cosimo de' Medici, while Botticelli received commissions from different members of the Medici lineage, leading to the artistic flourishing of the Renaissance.