Question

The following are some statements regarding glycolysis,

choose the option with incorrect statements
a. glycolysis is not regulated by pyruvate kinase
b. lactate can be an end product of glycolysis
c. glycolysis cannot function anaerobically
d. in erythrocytes, the second site in glycolysis for atp generation can be bypassed

Answer 1

Glycolysis can function anaerobically and produce lactate as an end product.

Step-by-step explanation:

The incorrect statement regarding glycolysis is option c. Glycolysis cannot function anaerobically. Glycolysis is the metabolic pathway that breaks down glucose to produce energy, and it can occur both aerobically (in the presence of oxygen) and anaerobically (in the absence of oxygen). In anaerobic conditions, the end product of glycolysis is lactate or lactic acid, which is option b.

During vigorous exercise, glycolysis can occur anaerobically in muscle cells to provide energy. This is called anaerobic fermentation, and it helps generate ATP quickly when oxygen is limited. Additionally, erythrocytes are able to bypass the second ATP generation site in glycolysis through the Rapaport-Luebering cycle which adjusts the ATP balance and provides 2,3-diphosphoglycerate for hemoglobin function.