Question

hospital pharmacist received the following order for a patient7: Medication Order: Staphcillin, 750 mg IV every 4 hours The following product and procedures were followed: Product: 6-g vial Staphcillin Pharmacy Operations: Reconstitute vial with sterile water for injection to yield Staphcillin 500 mg/mL and further dilute in 100 mL of sodium chloride injection. Administer: 30-minute IV infusion. (a) How many milliliters of solution from the reconstituted vial should be used per infusion?

Answer 1

To calculate how many milliliters of solution from the reconstituted vial should be used per infusion, follow the given instructions. For each infusion, 1.5 mL of the reconstituted Staphcillin solution should be used.

Step-by-step explanation:

To calculate how many milliliters of solution from the reconstituted vial should be used per infusion, we need to follow the given instructions. First, reconstitute the 6-g vial of Staphcillin with sterile water for injection to yield Staphcillin 500 mg/mL. This means that for every 1 mL of reconstituted solution, there will be 500 mg of Staphcillin. Next, further dilute the reconstituted solution in 100 mL of sodium chloride injection. Finally, administer the solution as a 30-minute IV infusion.

Since the reconstituted solution has a concentration of 500 mg/mL, and we need to administer 750 mg of Staphcillin IV every 4 hours, we can calculate the required volume of solution per infusion as follows: 750 mg / 500 mg/mL = 1.5 mL.