Final answer:
A person with A- blood receiving O blood will generally not have any adverse reactions because O blood type is considered the universal donor, lacking A and B antigens that could cause immune response. The Rh factor also aligns in this scenario, as both are negative, preventing potential Rh incompatibility reactions.
Step-by-step explanation:
When a person with A- blood type receives blood from a donor with an O blood group, they receive what is known as the universal donor blood type. Since type O blood does not have A or B antigens on the red blood cells, the recipient's antibodies will not react against the donor blood, preventing any agglutination or clumping of cells. This ensures that the blood transfusion is safe and will not cause a transfusion reaction. This compatibility arises because type O blood has neither A nor B antigens on the red blood cells, and therefore can be given to patients with different blood types without causing an immune response.
However, it is also important to consider the Rh factor when performing transfusions. In this case, since the recipient is A- and the donor is O (presumed O- for the explanation), the Rh factor is compatible.
Problems could potentially occur if the recipient has antibodies against the O blood type or if the O blood donor has been exposed to Rh antigens and developed antibodies, but in practice, these situations are rare, and type O negative blood is typically safe to give to recipients with other negative blood types.