Final answer:
The code mystring[1] = 's' will not work because strings in Python are immutable, resulting in a TypeError. To change the string, you would have to create a new string using slicing and concatenation techniques.
Step-by-step explanation:
The student has asked about the outcome of attempting to change a character in a string in Python. In Python, strings are immutable, which means you cannot change a character directly by indexing. Trying to execute the code snippet mystring = "artwork"; mystring[1] = "s"; print(mystring) will result in a TypeError. However, if you want to alter the string, you have to create a new one. To replace the second character with 's', you could slice the string and concatenate like this: mystring = mystring[:1] + 's' + mystring[2:], which would change the string to 'asrwork'.