Final answer:
The primary target tissues for insulin do not include the liver, as it, along with the brain and intestine, does not primarily depend on insulin for glucose uptake, making the liver only the correct answer.
Step-by-step explanation:
The primary target tissues for insulin are largely comprised of muscle, the liver, and adipose tissue. The brain, liver, and intestine, though important organs with regard to glucose uptake and regulation, do not primarily rely on insulin to facilitate glucose entry into their cells. Specifically, the liver has a unique role in managing blood glucose levels and does not require insulin for glucose uptake. Therefore, the correct answer to the question "A primary target tissue for insulin is the" is A.) liver only.