Final answer:
Renal calculi, or kidney stones, commonly manifest as severe episodic pain in the flank, lower abdomen, and groin, known as renal colic. This pain is caused by the obstruction of the ureter due to the growth of kidney stones. Additional symptoms can include nausea, vomiting, and hematuria (bloody urine).
Step-by-step explanation:
A common manifestation of renal calculi, also known as kidney stones, is severe episodic pain in the flank, lower abdomen, and groin, which is referred to as renal colic. This pain occurs when kidney stones grow to a sufficient size and cause obstruction of the ureter, leading to dilation and stretching of the upper ureter and renal pelvis. Renal colic is often accompanied by nausea and vomiting, and hematuria (bloody urine) may also be present due to damage to the urinary tract lining.